Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877351 | 0.73 | HRH3 (0.52) | HRH3CYP2D6KDM4ELMNAMAPT | |
| SCHEMBL10605013 | 0.71 | SIGMAR1 (0.60) | GRIN2DGRIN3BADRA1DADRA1AADRA1B | |
| SCHEMBL6249126 | 0.70 | HRH3 (0.57) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL4229239 | 0.70 | HRH3 (0.44) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL471858 | 0.69 | KDM4E (0.60) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL7009247 | 0.69 | HRH3 (0.56) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL668560 | 0.68 | HRH3 (0.58) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL8958637 | 0.67 | HRH3 (0.57) | HRH3CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL18715834 | 0.67 | MEN1 (0.48) | HRH3SIGMAR1MEN1KMT2ADRD3 | |
| SCHEMBL8116743 | 0.66 | HRH3 (0.56) | HRH3CYP2D6KDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |