Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 11/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684017 | 0.80 | KCNJ11 (0.42) | KCNJ11AR | |
| SCHEMBL4683462 | 0.77 | KCNQ3 (0.45) | KCNJ11 | |
| SCHEMBL8854243 | 0.75 | ABCC9 (0.40) | KCNJ11CYP2C9 | |
| SCHEMBL4678745 | 0.73 | KDM4E (0.52) | KCNJ11 | |
| SCHEMBL18172150 | 0.72 | USP30 (0.60) | KCNJ11USP30TRPV1AR | |
| SCHEMBL4683574 | 0.72 | USP30 (0.43) | KCNJ11USP30TRPV1TRPV4AR | |
| SCHEMBL4683571 | 0.72 | USP30 (0.43) | KCNJ11USP30TRPV1TRPV4AR | |
| SCHEMBL29585632 | 0.71 | TRPV1 (0.49) | KCNJ11USP30TRPV1TRPV4CLK2 | |
| SCHEMBL2225852 | 0.71 | TRPV1 (0.49) | KCNJ11USP30TRPV1TRPV4CLK2 | |
| SCHEMBL10383508 | 0.71 | AR (0.46) | TRPV1ARSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392655-B1 | POTASSIUM CHANNEL OPENERS | ABBOTT LAB (US) | 2008-07-16 | — | — | EP | disclosed |