Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686233 | 0.79 | CYP3A4 (0.34) | LMNA | |
| SCHEMBL1718577 | 0.78 | CYP3A4 (0.36) | LMNA | |
| SCHEMBL4498845 | 0.75 | DRD3 (0.45) | — | |
| SCHEMBL5492084 | 0.72 | CNR2 (0.35) | HPGD | |
| SCHEMBL9911419 | 0.72 | KDM1A (0.36) | RAB9AHPGD | |
| SCHEMBL7065484 | 0.72 | KDM4E (0.36) | — | |
| SCHEMBL898008 | 0.70 | ALDH1A1 (0.43) | RAB9ALMNA | |
| SCHEMBL12550908 | 0.69 | MEN1 (0.34) | RAB9AHPGD | |
| SCHEMBL24625517 | 0.69 | HPGD (0.38) | HPGD | |
| Hydrochloric Acid SCHEMBL5889035 | 0.68 | ALDH1A1 (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381599-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-09-24 | — | — | EP | disclosed |