Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233632 | 0.86 | ABCG2 (0.45) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4232477 | 0.86 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4237437 | 0.86 | MAPT (0.50) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4683963 | 0.82 | KCNH2 (0.42) | KMT2AMAPTALDH1A1 | |
| SCHEMBL2812864 | 0.80 | NPSR1 (0.50) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4686461 | 0.80 | ALDH1A1 (0.40) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4687895 | 0.76 | MEN1 (0.60) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4233934 | 0.75 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6136613 | 0.75 | CYP1A2 (0.50) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15514870 | 0.75 | NPSR1 (0.48) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |