Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686461 | 0.89 | ALDH1A1 (0.40) | KCNH2ALDH1A1MAPTPOLBACHE | |
| SCHEMBL4686937 | 0.88 | POLB (0.43) | MAPTPOLBACHEKMT2APTGIR | |
| SCHEMBL4683665 | 0.82 | MEN1 (0.48) | ALDH1A1MAPTKMT2A | |
| SCHEMBL4745445 | 0.81 | MCHR1 (0.38) | ALDH1A1MAPTPOLBKMT2APTGIR | |
| SCHEMBL4233453 | 0.78 | ACHE (0.39) | KCNH2ALDH1A1MAPTKDM4EACHE | |
| SCHEMBL4234325 | 0.77 | ACHE (0.41) | KCNH2MAPTPOLBACHEKMT2A | |
| SCHEMBL4233730 | 0.76 | KCNH2 (0.36) | KCNH2ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL2812864 | 0.76 | NPSR1 (0.50) | ALDH1A1MAPTKMT2ATTR | |
| SCHEMBL4242218 | 0.71 | ACHE (0.42) | MAPTKDM4EPOLBACHEKMT2A | |
| SCHEMBL4233632 | 0.71 | ABCG2 (0.45) | ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |