Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.50 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 5/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689324 | 0.92 | CCR3 (0.44) | CCR3CCR2MEN1KMT2AFLT1 | |
| SCHEMBL4686596 | 0.92 | CCR3 (0.57) | CCR3CCR2OPRM1OPRD1MEN1 | |
| SCHEMBL4687050 | 0.90 | CCR3 (0.46) | CCR3CCR2FLT1KDRMAPT | |
| SCHEMBL4232306 | 0.90 | CCR3 (0.39) | CCR3OPRM1OPRD1MEN1ALDH1A1 | |
| SCHEMBL4687969 | 0.88 | CCR3 (0.39) | CCR3 | |
| SCHEMBL4688476 | 0.88 | CCR3 (0.51) | CCR3CCR2OPRM1OPRD1MEN1 | |
| SCHEMBL4686982 | 0.86 | CCR3 (0.49) | CCR3CCR2OPRM1OPRD1MEN1 | |
| SCHEMBL4689332 | 0.86 | CCR3 (0.42) | CCR3CCR2ALDH1A1FLT1KDR | |
| SCHEMBL4682566 | 0.86 | FGFR1 (0.42) | CCR3OPRM1OPRD1LMNAFLT1 | |
| SCHEMBL4689230 | 0.86 | CCR3 (0.42) | CCR3MEN1KMT2AFLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |