Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686982 | 0.91 | CCR3 (0.49) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4686596 | 0.90 | CCR3 (0.57) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4683722 | 0.90 | MAPT (0.49) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4683553 | 0.90 | CCR3 (0.49) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4684519 | 0.89 | MAPT (0.45) | CCR3MAPTHRH3MCHR2MCHR1 | |
| SCHEMBL4688687 | 0.89 | CCR3 (0.48) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4688148 | 0.88 | CCR3 (0.49) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4682983 | 0.88 | HRH3 (0.56) | CCR3MAPTLMNAHRH3 | |
| SCHEMBL4683919 | 0.88 | CCR3 (0.50) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4235491 | 0.87 | HRH3 (0.48) | MAPTOPRM1OPRD1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |