Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 2/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.39 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683919 | 0.88 | CCR3 (0.50) | CCR3 | |
| SCHEMBL4235502 | 0.86 | TAS1R3 (0.40) | BCL9CTNNB1KDM1ARCOR1 | |
| SCHEMBL4684667 | 0.85 | TOP2A (0.44) | BCL9CTNNB1EPHX2TOP2A | |
| SCHEMBL4689270 | 0.85 | BCL9 (0.45) | BCL9CTNNB1DDR2TOP2A | |
| SCHEMBL4683459 | 0.85 | MAPT (0.45) | TOP2ASMN1; SMN2 | |
| SCHEMBL4687771 | 0.83 | TOP2A (0.41) | BCL9CTNNB1KDM1AEPHX2TOP2A | |
| SCHEMBL4689324 | 0.81 | CCR3 (0.44) | CCR3 | |
| SCHEMBL4686596 | 0.80 | CCR3 (0.57) | CCR3 | |
| SCHEMBL4687050 | 0.79 | CCR3 (0.46) | CCR3 | |
| SCHEMBL4687031 | 0.78 | NAMPT (0.44) | BCL9CTNNB1EPHX2TOP2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |