Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.62 |
| ▸ | MEN1 | O00255 | 12/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683941 | 1.00 | KMT2A (0.62) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4686933 | 0.88 | KMT2A (0.65) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4686928 | 0.88 | KMT2A (0.65) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4687895 | 0.87 | MEN1 (0.60) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4687906 | 0.84 | MEN1 (0.58) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4687907 | 0.84 | MEN1 (0.58) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL5169615 | 0.81 | FFAR1 (0.69) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL5169625 | 0.81 | FFAR1 (0.69) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4684023 | 0.81 | MEN1 (0.60) | KMT2AMEN1LMNAMAPK1POLB | |
| SCHEMBL4684021 | 0.81 | MEN1 (0.60) | KMT2AMEN1LMNAMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |