Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.58 |
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MYOC | Q99972 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169615 | 1.00 | FFAR1 (0.69) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL22225262 | 0.89 | FFAR1 (0.73) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL3737969 | 0.88 | MEN1 (0.73) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL4690573 | 0.85 | MEN1 (0.79) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL2192999 | 0.84 | FFAR1 (0.60) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL10912746 | 0.84 | FFAR1 (0.62) | FFAR1KDM4ECRHBPCRHR2KMT2A | |
| SCHEMBL6392968 | 0.83 | MITF (0.69) | KMT2AMEN1MAPTNPC1MAPK1 | |
| SCHEMBL4686933 | 0.83 | KMT2A (0.65) | FFAR1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL4686928 | 0.83 | KMT2A (0.65) | FFAR1KMT2AMEN1MAPTNPC1 | |
| SCHEMBL2858917 | 0.82 | HSPB1 (0.54) | FFAR1KMT2AMEN1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |