Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 12/20 | 0.65 |
| ▸ | MEN1 | O00255 | 11/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | DDX3X | O00571 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686928 | 1.00 | KMT2A (0.65) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4683941 | 0.88 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4683934 | 0.88 | KMT2A (0.62) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4718987 | 0.87 | KMT2A (0.58) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4683454 | 0.86 | MEN1 (0.62) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4227907 | 0.84 | MEN1 (0.55) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4688634 | 0.84 | MEN1 (0.56) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL4688637 | 0.84 | MEN1 (0.56) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL5169615 | 0.83 | FFAR1 (0.69) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5169625 | 0.83 | FFAR1 (0.69) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |