Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 9/20 | 0.77 |
| ▸ | CDK4 | P11802 | 1/20 | 0.65 |
| ▸ | PRKACA | P17612 | 1/20 | 0.65 |
| ▸ | PRKACG | P22612 | 1/20 | 0.65 |
| ▸ | PRKACB | P22694 | 1/20 | 0.65 |
| ▸ | CCND1 | P24385 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 6/20 | 0.65 |
| ▸ | QPCT | Q16769 | 4/20 | 0.57 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676702 | 0.85 | CAMK2D (0.69) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL4679205 | 0.83 | CAMK2D (0.75) | CAMK2DGSK3BQPCT | |
| SCHEMBL7059398 | 0.83 | PIM1 (0.75) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL8163111 | 0.82 | PRKACA (0.74) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL8161270 | 0.81 | GSK3B (0.74) | CAMK2DCDK4CCND1GSK3B | |
| SCHEMBL4679346 | 0.81 | CAMK2D (0.68) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL4676697 | 0.80 | CAMK2D (0.67) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL9088139 | 0.79 | PRKACA (0.81) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL9086560 | 0.79 | PRKACA (0.81) | CAMK2DCDK4PRKACAPRKACGPRKACB | |
| SCHEMBL9148747 | 0.79 | PRKACA (1.00) | CAMK2DCDK4PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |