Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 9/20 | 0.69 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 7/20 | 0.50 |
| ▸ | QPCT | Q16769 | 6/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | PRKACG | P22612 | 1/20 | 0.48 |
| ▸ | PRKACB | P22694 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679205 | 0.92 | CAMK2D (0.75) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL4675948 | 0.90 | CAMK2D (0.57) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL4684095 | 0.85 | CAMK2D (0.77) | CAMK2DGSK3BQPCTCDK4PRKACA | |
| SCHEMBL4676697 | 0.84 | CAMK2D (0.67) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL4679346 | 0.82 | CAMK2D (0.68) | CAMK2DCDK2GSK3BQPCTCDK4 | |
| SCHEMBL2954182 | 0.82 | CAMK2D (0.65) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL13241407 | 0.81 | CCNT1 (0.70) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL13241411 | 0.80 | CCNT1 (0.76) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL13241410 | 0.79 | CCNT1 (0.74) | CAMK2DCCNT1CCNA2CDK2CDK9 | |
| SCHEMBL4675940 | 0.75 | CAMK2D (0.56) | CAMK2DCCNT1CCNA2CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |