Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680716 | 0.89 | MEN1 (0.50) | CASRLMNAGAAEPHX2MEN1 | |
| SCHEMBL14208451 | 0.84 | HDAC3 (0.46) | CASRLMNAGAAEPHX2MEN1 | |
| SCHEMBL16034079 | 0.82 | EPHX2 (0.52) | CASRLMNAGAAEPHX2HDAC3 | |
| SCHEMBL20377971 | 0.82 | EPHX2 (0.52) | CASRLMNAGAAEPHX2HDAC3 | |
| SCHEMBL20377967 | 0.82 | EPHX2 (0.52) | CASRLMNAGAAEPHX2HDAC3 | |
| SCHEMBL14428705 | 0.79 | CASR (0.55) | CASRLMNAGAAEPHX2HDAC3 | |
| SCHEMBL14063803 | 0.78 | CYP1A2 (0.50) | CASRLMNAGAAEPHX2MEN1 | |
| SCHEMBL4676209 | 0.76 | APAF1 (0.54) | CASRLMNAMEN1KMT2A | |
| SCHEMBL4676206 | 0.76 | APAF1 (0.54) | CASRLMNAMEN1KMT2A | |
| SCHEMBL9680229 | 0.76 | SMN1; SMN2 (0.54) | CASRLMNAGAAEPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945448-B1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES (JP) | 2008-11-26 | — | — | EP | disclosed |
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |