Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.48 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 2/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689244 | 0.91 | CCR3 (0.49) | MCHR1MCHR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4233974 | 0.89 | SMN1; SMN2 (0.44) | MCHR1MCHR2SMN1; SMN2NPSR1CCR3 | |
| SCHEMBL4689248 | 0.89 | MCHR1 (0.45) | MCHR1MCHR2USP2LMNAMAPT | |
| SCHEMBL4688728 | 0.87 | MCHR1 (0.47) | MCHR1MCHR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4683563 | 0.86 | CCR3 (0.47) | MCHR1MCHR2MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4683061 | 0.85 | MCHR1 (0.45) | MCHR1MCHR2MAPTHTTSMN1; SMN2 | |
| SCHEMBL4683393 | 0.85 | FGFR1 (0.48) | MCHR1MCHR2LMNAMAPTHTT | |
| SCHEMBL4683553 | 0.84 | CCR3 (0.49) | MCHR1MCHR2USP2LMNAMAPT | |
| SCHEMBL4683722 | 0.83 | MAPT (0.49) | MCHR1MCHR2LMNAMAPTHTT | |
| SCHEMBL4687404 | 0.83 | MCHR1 (0.47) | MCHR1MCHR2LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |