Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.46 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687195 | 0.94 | CCR3 (0.47) | CCR3MCHR1MCHR2QPCTHTR2A | |
| SCHEMBL4688202 | 0.93 | CCR3 (0.44) | CCR3MCHR1MCHR2HTR2AHTR3A | |
| SCHEMBL4689244 | 0.92 | CCR3 (0.49) | CCR3MCHR1MCHR2SMN1; SMN2NPSR1 | |
| SCHEMBL4687050 | 0.90 | CCR3 (0.46) | CCR3MCHR1MCHR2HTR2AKDR | |
| SCHEMBL4233399 | 0.90 | SMN1; SMN2 (0.43) | CCR3MCHR1MCHR2SMN1; SMN2NPSR1 | |
| SCHEMBL4688345 | 0.89 | CCR3 (0.46) | CCR3MCHR1MCHR2QPCTHTR2A | |
| SCHEMBL4688728 | 0.88 | MCHR1 (0.47) | CCR3MCHR1MCHR2SMN1; SMN2NPSR1 | |
| SCHEMBL4687903 | 0.88 | CCR3 (0.43) | CCR3MCHR1MCHR2HTR2AHTR3A | |
| SCHEMBL4684906 | 0.86 | MCHR1 (0.48) | CCR3MCHR1MCHR2SMN1; SMN2NPSR1 | |
| SCHEMBL4683061 | 0.86 | MCHR1 (0.45) | CCR3MCHR1MCHR2SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |