Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4678464 | 0.89 | ALDH1A1 (0.67) | AKR1C3TDP1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL10453196 | 0.88 | AKR1C3 (0.57) | AKR1C3TDP1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL28384877 | 0.81 | AKR1C3 (0.85) | AKR1C3TDP1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL11189754 | 0.81 | AKR1C3 (0.84) | AKR1C3TDP1ALDH1A1KMT2ALMNA | |
| SCHEMBL8923851 | 0.81 | AKR1C3 (0.57) | AKR1C3TDP1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL2047090 | 0.79 | CYP2C19 (0.66) | AKR1C3ALDH1A1KMT2ANPSR1LMNA | |
| SCHEMBL29701296 | 0.78 | AKR1C3 (1.00) | AKR1C3TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL3940689 | 0.78 | ALDH1A1 (0.67) | AKR1C3ALDH1A1KMT2ANPSR1TP53 | |
| SCHEMBL503364 | 0.78 | AKR1C3 (1.00) | AKR1C3TDP1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL15823215 | 0.78 | DHODH (0.73) | TDP1ALDH1A1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | claimed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | claimed |
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |