Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 10/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647690 | 1.00 | NR3C1 (0.47) | NR3C1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4646109 | 0.92 | NR3C1 (0.47) | NR3C1NR3C2PGRNEK1KMT2A | |
| SCHEMBL4645653 | 0.88 | NR3C1 (0.46) | NR3C1NR3C2PGRMMP2MMP9 | |
| SCHEMBL4648789 | 0.88 | NR3C1 (0.49) | NR3C1NR3C2PGRNEK1MMP2 | |
| SCHEMBL4648410 | 0.88 | NEK1 (0.56) | NR3C1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4645638 | 0.84 | NR3C1 (0.42) | NR3C1NR3C2PGRNEK1MMP2 | |
| SCHEMBL14025309 | 0.83 | NEK1 (0.50) | NR3C1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4646409 | 0.82 | MEN1 (0.47) | NR3C1NR3C2PGRNEK1MMP2 | |
| SCHEMBL4687933 | 0.82 | MEN1 (0.47) | NR3C1NR3C2PGRNEK1MMP2 | |
| SCHEMBL14064843 | 0.82 | KMT2A (0.45) | NR3C1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964834-A1 | Sulphonyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |