Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | CFTR | P13569 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | GAA | P10253 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31758437 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| Hydrochloric Acid SCHEMBL27808204 | 0.98 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL8416022 | 0.89 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRKDM4EGAA | |
| SCHEMBL29434198 | 0.88 | BRD4 (0.59) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL70381 | 0.88 | BRD4 (0.59) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL1025155 | 0.85 | IDO1 (0.47) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL5749605 | 0.83 | ATM (0.56) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL31049726 | 0.81 | BRD4 (0.53) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL31049722 | 0.81 | BRD4 (0.53) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL5750893 | 0.81 | BRD4 (0.53) | ALDH1A1HSD17B10CFTRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102361863-B | Novel bicyclic antibiotics | BASILEA PHARMACEUTICA AG | 2014-12-03 | — | — | CN | disclosed |
| CN-102143940-B | Cyclohexyl amide derivatives as CRF-1 receptor antagonists and uses thereof | NOVARTIS AG | 2014-04-16 | — | — | CN | disclosed |
| CN-102361863-A | Novel bicyclic antibiotics | BASILEA PHARMACEUTICA AG | 2012-02-22 | — | — | CN | disclosed |
| CN-101146768-B | Method for producing sulfamate-carboxylate derivative | SHIONOGI & CO | 2012-01-25 | — | — | CN | disclosed |
| CN-101421251-B | 4,5-diphenyl-pyrimidinyl-amino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND | 2011-10-19 | — | — | CN | disclosed |
| CN-102105485-A | Selective caspase inhibitors and uses thereof | NEW WORLD LAB INC | 2011-06-22 | — | — | CN | disclosed |
| CN-102056918-A | Pyrrolidine ether derivatives as NK3 receptor antagonists | HOFFMANN LA ROCHE | 2011-05-11 | — | — | CN | disclosed |
| CN-101421251-A | 4,5-diphenyl-pyrimidinyl-amino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND (FR) | 2009-04-29 | — | — | CN | disclosed |
| EP-1236712-B1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | AJINOMOTO KK (JP) | 2008-08-06 | — | — | EP | disclosed |
| CN-101146768-A | Method for producing sulfamate-carboxylate derivative | SHIONOGI & CO (JP) | 2008-03-19 | — | — | CN | disclosed |
| US-6992102-B2 | Bicyclic modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-01-31 | — | — | US | disclosed |
| US-20040092559-A1 | Bicyclic modulators of androgen receptor function | HAMANN LAWRENCE (US) | 2004-05-13 | — | — | US | disclosed |
| EP-1414795-A1 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2004-05-06 | — | — | EP | disclosed |
| US-6710056-B2 | PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. | AJINOMOTO CO., INC. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-6670386-B2 | For therapy of nuclear hormone receptor-associated conditions, such as age related diseases, for example sarcopenia | BRISTOL-MYERS SQUIBB COMPANY | 2003-12-30 | — | — | US | disclosed |
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | AJINOMOTO CO. INC (JP) | 2003-06-12 | — | — | US | disclosed |
| US-20030055094-A1 | Bicyclic modulators of androgen receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2003-03-20 | — | — | US | disclosed |
| WO-2003011824-A1 | BICYCLIC MODULATORS OF ANDROGEN RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-13 | — | — | WO | disclosed |
| EP-1236712-A1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| CN-1305454-A | Anthranilic acid derivatives as inhibitors of CGMP phosphodiesterase | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | HABP2, F2, F7 | ALDH1A1 622/4885HSD17B10 1277/4885CFTR 4164/4885 |
| US-20030055094-A1 | Bicyclic modulators of androgen receptor function | AR, NR5A1, ESRRA | ALDH1A1 763/4885HSD17B10 106/4885CFTR 3149/4885 |
| US-20040092559-A1 | Bicyclic modulators of androgen receptor function | AR, NR5A1, ESRRA | ALDH1A1 763/4885HSD17B10 106/4885CFTR 3149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.