Sugi Predict

Sugi Predict / Compounds / SCHEMBL5750893

SCHEMBL5750893

SCHEMBL5750893

COC(=O)c1ccc(C(=O)O)c2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 2/20 0.53
▸ KDM4E B2RXH2 6/20 0.53
▸ ALDH1A1 P00352 4/20 0.53
▸ LMNA P02545 3/20 0.53
▸ TSHR P16473 2/20 0.52
▸ NR4A2 P43354 4/20 0.51
▸ CREBBP Q92793 1/20 0.51
▸ CDC25B P30305 1/20 0.51
▸ CFTR P13569 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ MAPT P10636 1/20 0.49
▸ ALOX15 P16050 1/20 0.49
▸ POLB P06746 1/20 0.48
▸ ATM Q13315 1/20 0.48
▸ NR4A1 P22736 1/20 0.48
▸ NR4A3 Q92570 1/20 0.48
▸ KMT2A Q03164 2/20 0.47
▸ THRB P10828 1/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3230050 0.92 NR4A2 (0.53) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL70381 0.92 BRD4 (0.59) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL29434198 0.92 BRD4 (0.59) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL31049722 0.84 BRD4 (0.53) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL31049726 0.84 BRD4 (0.53) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL982076 0.84 BRD4 (0.53) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL31284375 0.83 NR4A1 (0.52) KDM4EALDH1A1TSHRNR4A2CDC25B
SCHEMBL70429 0.83 LMNA (0.59) BRD4KDM4EALDH1A1LMNATSHR
SCHEMBL29406630 0.82 NR4A1 (0.65) KDM4EALDH1A1TSHRNR4A2CDC25B
SCHEMBL28798 0.82 NR4A1 (0.65) KDM4EALDH1A1TSHRNR4A2CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115246923-A Wide-color-gamut high-performance fluorescent copolyester and synthesis method and application thereof 中国科学院化学研究所 2022-10-28 — — CN claimed
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 — — US disclosed
CN-118930402-A Preparation method of 4-acetyl-1-naphthoic acid 江苏凌云药业股份有限公司 2024-11-12 — — CN disclosed
WO-2023226835-A1 POLYESTER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 珠海金发生物材料有限公司 2023-11-30 — — WO disclosed
CN-115448831-B Process for preparing 4-acetyl-1-naphthoic acid 北京元延医药科技股份有限公司 2023-02-03 — — CN disclosed
CN-115246923-A Wide-color-gamut high-performance fluorescent copolyester and synthesis method and application thereof 中国科学院化学研究所 2022-10-28 — — CN disclosed
CN-113354530-A Method for preparing 4-acetyl-1-naphthoic acid 东莞市东阳光动物保健药品有限公司 2021-09-07 — — CN disclosed
US-10961202-B2 Bis-benzimidazole compounds and methods of using the same THE SCRIPPS RESEARCH INSTITUTE (US) 2021-03-30 — — US disclosed
CN-111333512-A Preparation of Aforana key intermediate 4-acetyl-1-naphthoate 江苏君若药业有限公司 2020-06-26 — — CN disclosed
CN-110167930-A ROR gamma modulators 百时美施贵宝公司 2019-08-23 — — CN disclosed
US-20090176822-A1 PYRROLIDINE INHIBITORS OF IAP GENENTECH, INC. (US) 2009-07-09 — — US disclosed
US-20060205772-A1 Amide derivatives and their use as inhibitors of 11-beta-hydroxysteroid dehydrogenase type I COPPOLA GARY M 2006-09-14 — — US disclosed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 — — CN disclosed
US-6982348-B2 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-01-03 — — US disclosed
US-20040127574-A1 Aminoethanol derivatives TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-07-01 — — US disclosed
EP-1362846-A1 AMINOETHANOL DERIVATIVES Takeda Chemical Industries, Ltd. (JP) 2003-11-19 — — EP disclosed
US-6232290-B1 FUNGICIDES AGAINST PNEUMOCYSTIS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-05-15 — — US disclosed
EP-1053247-A1 ANTIFUNGAL CYCLOHEXAPEPTIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-11-22 — — EP disclosed
WO-1999040108-A1 NEW COMPOUND FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1999-08-12 — — WO disclosed
US-4304569-A Formulation for brightening synthetic fibers and its preparation and use CASSELLA AG. (DE) 1981-12-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 BRD4 1127/4885KDM4E 2776/4885ALDH1A1 2378/4885
US-10961202-B2 Bis-benzimidazole compounds and methods of using the same HNRNPH1, HNRNPH3, HNRNPUL2 BRD4 255/4885KDM4E 1792/4885ALDH1A1 3412/4885
US-20040127574-A1 Aminoethanol derivatives CETP, LCAT, MTTP BRD4 461/4885KDM4E 244/4885ALDH1A1 783/4885
US-20090176822-A1 PYRROLIDINE INHIBITORS OF IAP BIRC5, XIAP, BIRC2 BRD4 203/4885KDM4E 1788/4885ALDH1A1 4197/4885
US-20060205772-A1 Amide derivatives and their use as inhibitors of 11-beta-hydroxysteroid dehydrogenase type I HSD11B1, HSD11B2, CYP11B1 BRD4 3881/4885KDM4E 1912/4885ALDH1A1 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.