SCHEMBL468559

SCHEMBL468559

C=C(C)O[Si](C)(Cl)OC(=C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147872 0.76
SCHEMBL204621 0.73 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL532363 0.73 HSD17B10 (0.33) HSD17B10TDP1
SCHEMBL550387 0.69 HSD17B10 (0.35) HSD17B10TDP1
SCHEMBL7793941 0.69 ALDH1A1 (0.37) HSD17B10TDP1
SCHEMBL450126 0.67
SCHEMBL9576404 0.67
SCHEMBL6943765 0.67 HSD17B10 (0.35) HSD17B10TDP1
SCHEMBL600083 0.67 ALDH1A1 (0.35)
SCHEMBL10638758 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2857436-B1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORP (JP) 2019-10-09 EP disclosed
US-9969843-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2018-05-15 US disclosed
US-9803052-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2017-10-31 US disclosed
US-20170051108-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-23 US disclosed
US-20170044314-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME KANEKA CORPORATION (JP) 2017-02-16 US disclosed
US-9505879-B2 Polymer having terminal structure including plurality of reactive silicon groups, method for manufacturing same, and use for same KANEKA CORPORATION (JP) 2016-11-29 US disclosed
US-9249262-B2 Curable organic polymer and method for production thereof, and curable composition containing the same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
EP-2386561-B1 Methods for producing alkoxyhydrosilanes KANEKA CORP (JP) 2016-01-13 EP disclosed
EP-2392600-B1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer KANEKA CORP (JP) 2015-12-23 EP disclosed
EP-2586784-B1 METHOD FOR PRODUCING ALKOXY HYDROSILANE KANEKA CORP (JP) 2015-12-09 EP disclosed
EP-2857436-A1 POLYMER HAVING TERMINAL STRUCTURE INCLUDING PLURALITY OF REACTIVE SILICON GROUPS, METHOD FOR MANUFACTURING SAME, AND USE FOR SAME Kaneka Corporation (JP) 2015-04-08 EP disclosed
EP-2586784-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
EP-2586783-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF KANEKACORPORATION (JP) 2012-08-02 US disclosed
EP-2392600-A1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer Kaneka Corporation (JP) 2011-12-07 EP disclosed
EP-2386561-A1 Methods for producing alkoxyhydrosilanes Kaneka Corporation (JP) 2011-11-16 EP disclosed
US-8039142-B2 Battery case SONY CORPORATION (JP) 2011-10-18 US disclosed
US-20110207886-A1 Method for Producing a-hereto-Substituted Alkylhalohydrosilane and Use Thereof KANEKA CORPORATION (JP) 2011-08-25 US disclosed
EP-2308884-A1 METHOD FOR PRODUCING -HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF Kaneka Corporation (JP) 2011-04-13 EP disclosed
US-20090247712-A1 CURABLE ORGANIC POLYMER AND METHOD FOR PRODUCTION THEREOF, AND CURABLE COMPOSITION CONTAINING THE SAME KANEKA CORPORATION (JP) 2009-10-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF ARSA, HACL2, AS3MT HSD17B10 422/4885TDP1 4009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.