SCHEMBL7793941

SCHEMBL7793941

CC(=O)O[Si](C)(Cl)OC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
HSD17B10 Q99714 2/20 0.30
LMNA P02545 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7059083 0.86
SCHEMBL7759623 0.84 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL7053117 0.81
SCHEMBL7795356 0.81
SCHEMBL7053335 0.80 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10LMNA
SCHEMBL10777409 0.78 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL10773422 0.78 ALDH1A1 (0.39) ALDH1A1TSHRHSD17B10LMNATDP1
SCHEMBL7761298 0.78
Cyclopropane SCHEMBL8991851 0.75 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL5361795 0.73 ALDH1A1 (0.41) ALDH1A1TSHRHSD17B10LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0694553-B1 Process for preparing acyloxysilanes DOW CORNING (US) 2001-11-28 EP disclosed
EP-0694553-A2 Process for preparing acyloxysilanes DOW CORNING CORPORATION (US) 1996-01-31 EP disclosed
US-5387706-A Contacting chlorosilane with carboxylic acid in film, forming acyloxysilane and hydrogen chloride, vaporizing hydrogen chloride, recovering acyloxysilane DOW CORNING CORPORATION (US) 1995-02-07 US disclosed