Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | NMT1 | P30419 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686119 | 1.00 | MMP1 (0.55) | MMP1MMP2MMP9EGFRNMT1 | |
| SCHEMBL3035626 | 0.93 | MMP1 (0.61) | MMP1MMP2MMP9EGFRNMT1 | |
| SCHEMBL3035627 | 0.93 | MMP1 (0.61) | MMP1MMP2MMP9EGFRNMT1 | |
| SCHEMBL4648073 | 0.83 | MAPT (0.56) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL3986444 | 0.83 | MAPT (0.56) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL9277123 | 0.83 | MAPT (0.56) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL3037269 | 0.81 | NMT1 (0.51) | MMP1MMP2MMP9EGFRNMT1 | |
| SCHEMBL3037270 | 0.81 | NMT1 (0.51) | MMP1MMP2MMP9EGFRNMT1 | |
| SCHEMBL4648144 | 0.81 | EGFR (0.64) | MMP1MMP2MMP9EGFRALDH1A1 | |
| SCHEMBL9989205 | 0.81 | EGFR (0.64) | MMP1MMP2MMP9EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957459-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063702-A2 | IMINOPROPENE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |