⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685867 | 0.91 | CAPN1 (0.44) | — | |
| SCHEMBL3261127 | 0.77 | — | — | |
| SCHEMBL2003673 | 0.77 | — | — | |
| SCHEMBL5662539 | 0.77 | — | — | |
| SCHEMBL1231894 | 0.77 | — | — | |
| SCHEMBL150899 | 0.77 | — | — | |
| SCHEMBL724247 | 0.76 | CAPN1 (0.46) | — | |
| SCHEMBL156217 | 0.75 | — | — | |
| SCHEMBL981785 | 0.74 | PTGS2 (0.48) | — | |
| SCHEMBL982395 | 0.74 | PTGS2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| EP-1023044-B1 | APATITE-COATED SOLID COMPOSITION | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-02-04 | — | — | EP | disclosed |
| EP-0949927-B1 | PHARMACEUTICAL COMPOSITION CONTAINING OSTEOGENESIS-PROMOTING SUBSTANCE AND A POLYETHYLENE GLYCOL | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-16 | — | — | EP | disclosed |
| EP-1208850-A1 | PASTES WITH THE SUSTAINED RELEASE OF OSTEOGENESIS PROMOTER | Takeda Chemical Industries, Ltd. (JP) | 2002-05-29 | — | — | EP | disclosed |
| US-6344209-B1 | BIODEGRADABLE POLYLACTIC ACID, POLYGLYCOLIC ACID AND COPOLYMERS OF THE TWO FOR BONE DISEASES THERAPY; ANTIBIOTICS, ANTI-INFLAMMATORY AND ANTI-TUMOR AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1120122-A1 | BONE REPAIR MATERIALS/ARTIFICIAL BONE COMPOSITIONS | Takeda Chemical Industries, Ltd. (JP) | 2001-08-01 | — | — | EP | disclosed |
| EP-0460488-B1 | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| EP-1105140-A2 | BENZOTHIEPINE COMPOUNDS AS ENHANCER OF CELL DIFFERENTIATION INDUCTION FACTOR | Takeda Chemical Industries, Ltd. (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-1087774-A2 | COMPOSITIONS FOR TREATING CARTILAGE DISEASE COMPRISING CERTAIN SULFUR-CONTAINING HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5371098-A | Use of oxazole compounds to treat osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
| EP-0376197-B1 | Sulfur-containing heterocyclic compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5239080-A | Oxazole compounds and their use as antidiabetic and bone-reduction inhibitory agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5158943-A | Osteoporosis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| EP-0460488-A1 | Sulfur-containing heterocyclic compounds | Takeda Chemical Industries, Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-5071841-A | For prevention of bone reabsorption | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0440183-A1 | Oxazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-07 | — | — | EP | disclosed |
| EP-0382199-A1 | Oxazole compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-08-16 | — | — | EP | disclosed |
| EP-0376197-A1 | Sulfur-containing heterocyclic compounds | Takeda Chemical Industries, Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |