⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667225 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL6864414 | 0.78 | — | — | |
| SCHEMBL9051664 | 0.78 | — | — | |
| SCHEMBL26111413 | 0.77 | — | — | |
| Ammonia Solution, Strong SCHEMBL29207984 | 0.77 | MEN1 (0.40) | — | |
| SCHEMBL7263481 | 0.77 | — | — | |
| SCHEMBL2666833 | 0.77 | — | — | |
| SCHEMBL27935793 | 0.77 | SLC6A3 (0.45) | — | |
| SCHEMBL20093101 | 0.76 | TLR7 (0.38) | — | |
| SCHEMBL861151 | 0.75 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028365-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC (US) | 2026-01-29 | — | — | US | disclosed |
| EP-4554938-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | Biogen MA Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| US-20240276957-A1 | METHODS OF TREATMENT WITH AMINOLEVULINIC ACID SYNTHASE 2 (ALAS2) MODULATORS | AGIOS PHARMACEUTICALS, INC. | 2024-08-22 | — | — | US | disclosed |
| CN-117964547-A | Urea compound and application thereof as Sigma2 and 5HT2A dual-target inhibitor | 瀚远医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2024067304-A1 | COMPOUND WITH INHIBITORY ACTIVITY AGAINST SIGMA2 AND 5HT2A AND USE | 瀚远医药有限公司 | 2024-04-04 | — | — | WO | disclosed |
| WO-2024015497-A1 | TYROSINE KINASE 2 INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-20230002408-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2023-01-05 | — | — | US | disclosed |
| CN-110964023-B | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |
| EP-4077305-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| CN-103261194-A | Oxazolyl-methyl ether derivatives as ALX receptor agonists | ACTELION PHARMACEUTICALS LTD | 2013-08-21 | — | — | CN | disclosed |
| WO-2012077049-A1 | OXAZOLYL-METHYLETHER DERIVATIVES AS ALX RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-14 | — | — | WO | disclosed |
| EP-1554274-B1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LTD (GB) | 2008-12-24 | — | — | EP | disclosed |
| US-7304087-B2 | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2007-12-04 | — | — | US | disclosed |
| US-7304087-B2 | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2007-12-04 | — | — | US | disclosed |
| US-7304087-B2 | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2007-12-04 | — | — | US | disclosed |
| US-20060258720-A1 | 1-Acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LIMITED (GB) | 2006-11-16 | — | — | US | disclosed |
| CN-1732165-A | 1-acyl-pyrrolidine derivatives for the treatment of viral infections | GLAXO GROUP LTD (GB) | 2006-02-08 | — | — | CN | disclosed |
| EP-1554274-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004037818-A1 | 1-ACYL-PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | GLAXO GROUP LIMITED (GB) | 2004-05-06 | — | — | WO | disclosed |