Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.47 |
| ▸ | HTR2A | P28223 | 10/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3568100 | 0.83 | HTR6 (0.57) | HTR6METSLC6A2HTR2AHTR2C | |
| SCHEMBL3561933 | 0.83 | SLC6A2 (0.64) | HTR6METSLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL3574163 | 0.82 | SLC6A2 (0.63) | HTR6METSLC6A2HTR2A | |
| SCHEMBL3574946 | 0.80 | SLC6A2 (0.68) | HTR6METSLC6A2HTR2AHTR2C | |
| SCHEMBL3568655 | 0.80 | SLC6A2 (0.67) | HTR6METSLC6A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3565513 | 0.79 | SLC6A2 (0.65) | HTR6METSLC6A2HTR2AHTR2C | |
| SCHEMBL13544520 | 0.78 | HTR6 (0.48) | HTR6METSLC6A2HTR2AHTR2C | |
| SCHEMBL3570695 | 0.78 | SLC6A2 (0.68) | HTR6SLC6A2HTR2AHTR2CKCNH2 | |
| SCHEMBL3564086 | 0.78 | SLC6A2 (0.57) | HTR6METSLC6A2HTR2A | |
| SCHEMBL3567470 | 0.78 | SLC6A2 (0.70) | HTR6METSLC6A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | claimed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | claimed |