Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 8/20 | 0.40 |
| ▸ | KDM5A | P29375 | 7/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | KDM5C | P41229 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4236364 | 0.90 | KDM4C (0.42) | CYP1A2KDM4CKDM5APHF8KDM5C | |
| SCHEMBL13568563 | 0.84 | CYP1A2 (0.40) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL2806347 | 0.82 | PHF8 (0.48) | KDM4CKDM5APHF8KDM2AKDM5C | |
| SCHEMBL22278957 | 0.78 | KDM5A (0.47) | MGAMGAASIMGAM2KMT2A | |
| SCHEMBL7416988 | 0.78 | KDM4C (0.51) | MEN1KMT2ASMN1; SMN2CYP1A2KDM4C | |
| SCHEMBL4788929 | 0.78 | MEN1 (0.60) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL22278980 | 0.76 | GAA (0.43) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL3903055 | 0.76 | DNM1 (0.50) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL3902356 | 0.76 | MEN1 (0.48) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL363334 | 0.75 | MGAM (0.55) | MGAMGAASIMGAM2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |