SCHEMBL2806347

SCHEMBL2806347

CN(C)N(CCC(=O)O)CCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PHF8 Q9UPP1 5/20 0.48
▸ KDM2A Q9Y2K7 5/20 0.48
▸ KDM7A Q6ZMT4 2/20 0.46
▸ EGLN1 Q9GZT9 3/20 0.42
▸ LMNA P02545 2/20 0.42
▸ ALKBH5 Q6P6C2 1/20 0.42
▸ SUCNR1 Q9BXA5 1/20 0.42
▸ FFAR3 O14843 1/20 0.41
▸ HDAC3 O15379 1/20 0.41
▸ HDAC1 Q13547 1/20 0.41
▸ HDAC2 Q92769 1/20 0.41
▸ HDAC8 Q9BY41 1/20 0.41
▸ KDM6B O15054 2/20 0.41
▸ KDM5C P41229 2/20 0.41
▸ KDM4A O75164 11/20 0.41
▸ KDM4C Q9H3R0 11/20 0.41
▸ KDM5A P29375 1/20 0.41
▸ SLC15A2 Q16348 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ ALDH2 P05091 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4686735 0.82 MGAM (0.45) PHF8KDM2AEGLN1KDM6BKDM5C
SCHEMBL1281503 0.78 PHF8 (0.48) PHF8KDM2AKDM7AEGLN1LMNA
SCHEMBL30498495 0.77 — —
SCHEMBL30498494 0.77 — —
SCHEMBL718216 0.77 KMT2A (0.56) PHF8KDM2AKDM7AEGLN1LMNA
SCHEMBL103874 0.77 — —
Water SCHEMBL29169413 0.76 PHF8 (0.46) PHF8KDM2AKDM7AEGLN1LMNA
Water SCHEMBL29140095 0.76 PHF8 (0.46) PHF8KDM2AKDM7AEGLN1LMNA
SCHEMBL13727806 0.76 LTA4H (0.32) PHF8KDM2ALMNAALDH1A1KDM4E
SCHEMBL10905398 0.75 PHF8 (0.41) PHF8KDM2AKDM7AEGLN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US claimed
US-11559474-B2 Hair lightening compositions and methods of use L'OREAL (FR) 2023-01-24 — — US disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 — — US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 — — US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 — — US disclosed
WO-2009144221-A1 PROCESS FOR PREPARING 3-(2,2- DIMETHYLHYDRAZINO) METHYLPROPIONATE GRINDEKS, A JOINT STOCK COMPANY (LV) 2009-12-03 — — WO disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 PHF8 375/4885KDM2A 1877/4885KDM7A 1523/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB PHF8 612/4885KDM2A 2020/4885KDM7A 607/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA PHF8 301/4885KDM2A 930/4885KDM7A 519/4885
US-11559474-B2 Hair lightening compositions and methods of use TYR, ALAD, CYBA PHF8 442/4885KDM2A 1849/4885KDM7A 953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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