Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854525 | 0.93 | IDO1 (0.43) | CTSLCTSKIDO1TDO2CTSS | |
| SCHEMBL4854521 | 0.93 | IDO1 (0.43) | CTSLCTSKIDO1TDO2CTSS | |
| SCHEMBL4854530 | 0.93 | IDO1 (0.43) | CTSLCTSKIDO1TDO2CTSS | |
| SCHEMBL4685497 | 0.90 | USP2 (0.37) | KLK5IDO1CCKARCCKBREPHX2 | |
| SCHEMBL7166021 | 0.89 | ACE (0.47) | CTSLCTSKKLK7KLK5IDO1 | |
| SCHEMBL7363235 | 0.89 | KLK5 (0.42) | CTSLCTSKKLK7KLK5IDO1 | |
| SCHEMBL4853017 | 0.83 | ITGB3 (0.43) | IDO1TDO2 | |
| SCHEMBL4852776 | 0.83 | ITGB3 (0.43) | IDO1TDO2 | |
| SCHEMBL4680620 | 0.83 | ITGB3 (0.43) | IDO1TDO2 | |
| SCHEMBL7169155 | 0.82 | ITGB3 (0.46) | CTSLCTSKIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594853-B1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |