Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 12/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.42 |
| ▸ | ITGAV | P06756 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854521 | 1.00 | IDO1 (0.43) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL4854530 | 1.00 | IDO1 (0.43) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL4686769 | 0.93 | CTSL (0.40) | IDO1TDO2CTSLCTSKCTSS | |
| SCHEMBL7166021 | 0.92 | ACE (0.47) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL4852776 | 0.90 | ITGB3 (0.43) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL4853017 | 0.90 | ITGB3 (0.43) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL4680620 | 0.90 | ITGB3 (0.43) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL7169155 | 0.89 | ITGB3 (0.46) | IDO1TDO2ITGB3ITGA2BITGAV | |
| SCHEMBL7167643 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BITGAV | |
| SCHEMBL7363235 | 0.85 | KLK5 (0.42) | IDO1CTSLCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371854-B2 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20060142568-A1 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MEREK PATENT GMBH (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142568-A1 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | ITGA1, ITGB1, ITGA2 | IDO1 487/4885TDO2 1861/4885ITGB3 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.