Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686834 | 0.92 | CCR3 (0.43) | QPCTCCR3KDRMEN1KMT2A | |
| SCHEMBL4688941 | 0.90 | CCR3 (0.41) | QPCTCCR3KDRSMN1; SMN2NPSR1 | |
| SCHEMBL4688912 | 0.90 | QPCT (0.39) | QPCTPDE4AKDRMEN1KMT2A | |
| SCHEMBL4226786 | 0.83 | SMN1; SMN2 (0.42) | CCR3MEN1KMT2AGAAMAPT | |
| SCHEMBL4687360 | 0.83 | CCR3 (0.43) | QPCTCCR3MEN1KMT2AGAA | |
| SCHEMBL4683109 | 0.82 | CCR3 (0.43) | QPCTCCR3MEN1KMT2AGAA | |
| SCHEMBL4687180 | 0.82 | CCR3 (0.41) | QPCTCCR3MEN1KMT2AGAA | |
| SCHEMBL4683361 | 0.81 | CCR3 (0.43) | QPCTCCR3KDRSMN1; SMN2NPSR1 | |
| SCHEMBL4686644 | 0.80 | MEN1 (0.40) | QPCTPDE4AKDRMEN1KMT2A | |
| SCHEMBL4240227 | 0.80 | SMN1; SMN2 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |