Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 5/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686834 | 0.95 | CCR3 (0.43) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4687180 | 0.92 | CCR3 (0.41) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4686897 | 0.90 | RAB9A (0.38) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4240227 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2NPSR1MCHR1CTSDMCHR2 | |
| SCHEMBL4687360 | 0.88 | CCR3 (0.43) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4683109 | 0.87 | CCR3 (0.43) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4688912 | 0.87 | QPCT (0.39) | QPCTKDR | |
| SCHEMBL4226786 | 0.86 | SMN1; SMN2 (0.42) | CCR3SMN1; SMN2NPSR1MCHR1CTSD | |
| SCHEMBL4683361 | 0.86 | CCR3 (0.43) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 | |
| SCHEMBL4687404 | 0.84 | MCHR1 (0.47) | CCR3SMN1; SMN2NPSR1QPCTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |