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SCHEMBL4687103

SCHEMBL4687103

Cc1ccc(S(=O)(=O)O)cc1CCCc1cccc2[nH]cc(S(=O)(=O)c3ccccc3)c12

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SLC6A2 P23975 16/20 0.60
▸ HTR2A P28223 15/20 0.60
▸ HTR2C P28335 1/20 0.56
▸ HTR6 P50406 1/20 0.56
▸ PTGER3 P43115 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4687106 0.84 SLC6A2 (0.63) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL4687105 0.83 SLC6A2 (0.64) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL3574952 0.80 SLC6A2 (0.73) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL4740842 0.80 SLC6A2 (0.60) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL4740844 0.80 SLC6A2 (0.60) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL3569005 0.78 SLC6A2 (0.73) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL3569288 0.78 SLC6A2 (0.76) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL4687102 0.77 SLC6A2 (0.47) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL3579639 0.76 SLC6A2 (0.60) SLC6A2HTR2AHTR2CHTR6PTGER3
SCHEMBL3566194 0.76 HTR2A (1.00) SLC6A2HTR2AHTR2CHTR6PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1973876-A2 SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS Wyeth (US) 2008-10-01 — — EP disclosed
WO-2007084841-A2 SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS WYETH (US) 2007-07-26 — — WO disclosed