Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.60 |
| ▸ | HTR2A | P28223 | 15/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740842 | 0.92 | SLC6A2 (0.60) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4744159 | 0.89 | SLC6A2 (0.48) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4744153 | 0.82 | SLC6A2 (0.48) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4687106 | 0.80 | SLC6A2 (0.63) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4687103 | 0.80 | SLC6A2 (0.60) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4743923 | 0.79 | SLC6A2 (0.37) | SLC6A2HTR2APKM | |
| SCHEMBL3569288 | 0.78 | SLC6A2 (0.76) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL3566194 | 0.76 | HTR2A (1.00) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL3574952 | 0.76 | SLC6A2 (0.73) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL3565077 | 0.75 | SLC6A2 (1.00) | SLC6A2HTR2AHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | disclosed |