Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 16/20 | 0.47 |
| ▸ | HTR2A | P28223 | 15/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687103 | 0.77 | SLC6A2 (0.60) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL8586535 | 0.73 | HTT (0.39) | — | |
| SCHEMBL28564255 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL4740842 | 0.69 | SLC6A2 (0.60) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4685487 | 0.69 | ALDH1A1 (0.34) | MEN1KMT2AGPR84 | |
| SCHEMBL4740844 | 0.69 | SLC6A2 (0.60) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL7525829 | 0.68 | HTT (0.33) | — | |
| SCHEMBL4687105 | 0.68 | SLC6A2 (0.64) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL4687106 | 0.67 | SLC6A2 (0.63) | SLC6A2HTR2AHTR2CHTR6PTGER3 | |
| SCHEMBL28246140 | 0.67 | MEN1 (0.52) | SLC6A2HTR2AHTR2CHTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973876-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | Wyeth (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007084841-A2 | SULFONYL SUBSTITUTED 1H-INDOLES AS LIGANDS FOR THE 5-HYDROXYTRYPTAMINE RECEPTORS | WYETH (US) | 2007-07-26 | — | — | WO | disclosed |