Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468723 | 0.83 | CPB2 (0.47) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL468721 | 0.83 | CPB2 (0.47) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL8707562 | 0.80 | CPB2 (0.45) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL8821909 | 0.80 | CPB2 (0.38) | CPB2GSRRNPEPFOLH1 | |
| SCHEMBL8708989 | 0.80 | CPB2 (0.38) | CPB2GSRRNPEPNOS2NOS3 | |
| SCHEMBL8716233 | 0.79 | RNPEP (0.40) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL8709649 | 0.78 | GSR (0.40) | CPB2GSRRNPEPFOLH1GABRR1 | |
| SCHEMBL7226730 | 0.78 | CPB2 (0.38) | CPB2GSRRNPEPFOLH1SLC6A5 | |
| SCHEMBL7224443 | 0.78 | CPB2 (0.41) | CPB2GSRRNPEPFOLH1NOS2 | |
| SCHEMBL7218411 | 0.78 | CPB2 (0.36) | CPB2GSRRNPEPFOLH1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032844-A9 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | — | 1997-12-24 | — | — | WO | disclosed |
| WO-1997032844-A1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-09-12 | — | — | WO | disclosed |