⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686394 | 0.83 | ALDH1A1 (0.62) | — | |
| SCHEMBL7205329 | 0.81 | EHMT2 (0.61) | — | |
| SCHEMBL679871 | 0.79 | ALDH1A1 (0.59) | — | |
| SCHEMBL11036195 | 0.78 | EHMT2 (0.64) | — | |
| SCHEMBL29956195 | 0.78 | ALDH1A1 (0.53) | — | |
| SCHEMBL4687627 | 0.78 | ALDH1A1 (0.57) | — | |
| Ethylene Glycol SCHEMBL3505769 | 0.77 | EHMT2 (0.77) | — | |
| SCHEMBL9259327 | 0.77 | — | — | |
| SCHEMBL12709500 | 0.77 | — | — | |
| SCHEMBL4687320 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102993250-B | -9-deoxidation-9A-azepine-9A-the a-homoerythromycin A derivatives that C-3 replaces | Luoyang Huizhong Animal Medicine Co., Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-103483154-A | Process for producing bisphenol compound | MITSUBISHI CHEM CORP | 2014-01-01 | — | — | CN | disclosed |
| CN-102993250-A | C-3 substituted-9-deoxidized-9A-aza-9A-high erythromycin A derivative | LUOYANG HUIZHONG ANIMAL MEDICINE CO LTD | 2013-03-27 | — | — | CN | disclosed |
| CN-102292311-A | Process for producing bisphenol compound | — | 2011-12-21 | — | — | CN | disclosed |
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |
| WO-2003106454-A1 | 1H-ISOQUINOLINE-OXAZOLIDINONE DERIVATIES AND THEIR USE AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-12-24 | — | — | WO | disclosed |
| CN-1100785-C | 1,3,4, 5-tetrahydrobenzo [ C ] azepine * -3-one disulfide derivatives and methods | MERVELL DOW PHARMACEUTICALS IN (US) | 2003-02-05 | — | — | CN | disclosed |
| CN-1046512-C | Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace | MERRELL DOW PHARMA (US) | 1999-11-17 | — | — | CN | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| CN-1143964-A | Pyrrolopyridazine derivative | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |
| CN-1142826-A | Novel mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace | MERRELL DOW PHARMA (US) | 1997-02-12 | — | — | CN | disclosed |
| CN-1140454-A | Novel mercaptoacetylamido-1,3,4,5-tetrahydro-benzo[c] azepin-3-one disulfide derivs. useful as inhibitors of enkephalinase and ACE | MERRELL DOW PHARMA (US) | 1997-01-15 | — | — | CN | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |