Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687627 | 0.94 | ALDH1A1 (0.57) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4684788 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4685852 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL4686394 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL10974209 | 0.82 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL29420551 | 0.81 | EHMT2 (0.55) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL1955246 | 0.81 | EHMT2 (0.55) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL7812414 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL422519 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 | |
| SCHEMBL8621148 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KMT2AMAPTEHMT2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110286935-A1 | Multi-Functional Nano-Device | ATRP Solutions, Inc. (US) | 2011-11-24 | — | — | US | disclosed |
| US-7786213-B2 | Biomacromolecule polymer conjugates | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-08-31 | — | — | US | disclosed |
| US-20070276088-A1 | Biomacromolecule Polymer Conjugates | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2007-11-29 | — | — | US | disclosed |
| US-7135466-B2 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-14 | — | — | US | disclosed |
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-09-21 | — | — | US | disclosed |
| WO-2005039641-A2 | BIOMACROMOLECULE POLYMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | KIRIN HOLDINGS KABUSHIKI KAISHA (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1243582-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES AND DRUGS CONTAINING THE SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211717-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | ALDH1A1 2003/4885KMT2A 2022/4885MAPT 4495/4885 |
| US-20040132727-A1 | Quinoline and quinazoline derivatives and drugs containing the same | PDGFRA, PDGFRB, PDGFA | ALDH1A1 2059/4885KMT2A 2006/4885MAPT 4476/4885 |
| US-20110286935-A1 | Multi-Functional Nano-Device | CD47, FCGRT, FCGR3B | ALDH1A1 2541/4885KMT2A 2450/4885MAPT 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.