Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | BCL9 | O00512 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683459 | 0.91 | MAPT (0.45) | TOP2AKDRMEN1KMT2AMAPT | |
| SCHEMBL4684667 | 0.90 | TOP2A (0.44) | TOP2AEPHX1BCL9CTNNB1HDAC1 | |
| SCHEMBL4688687 | 0.89 | CCR3 (0.48) | MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4234174 | 0.86 | PKM (0.43) | TOP2AFAAHEPHX2KDM1AMAOA | |
| SCHEMBL4687031 | 0.84 | NAMPT (0.44) | TOP2AKDRBCL9CTNNB1MEN1 | |
| SCHEMBL4687969 | 0.83 | CCR3 (0.39) | TOP2ABCL9CTNNB1SMN1; SMN2FAAH | |
| SCHEMBL4686982 | 0.83 | CCR3 (0.49) | MEN1KMT2AMAPT | |
| SCHEMBL4686839 | 0.82 | CCR3 (0.46) | MEN1KMT2AMAPTRAB9AEPHX2 | |
| SCHEMBL4687749 | 0.80 | EPHX1 (0.49) | EPHX1KDRHDAC1HDAC2KMT2A | |
| SCHEMBL4783961 | 0.80 | EPHX1 (0.49) | EPHX1KDRHDAC1HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |