SCHEMBL468796

SCHEMBL468796

CC(=O)NC(CC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
ALOX15 P16050 1/20 0.57
NFKB1 P19838 1/20 0.57
PTGS2 P35354 1/20 0.57
THPO P40225 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ALDH1A1 P00352 2/20 0.55
ECE1 P42892 2/20 0.54
ITGB2 P05107 2/20 0.47
ICAM1 P05362 2/20 0.47
ITGAL P20701 2/20 0.47
GNPAT O15228 1/20 0.46
CA2 P00918 4/20 0.45
CA1 P00915 3/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204312 1.00 KDM4E (0.57) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL468797 1.00 KDM4E (0.57) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL9438441 0.98 KDM4E (0.55) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL9438442 0.98 KDM4E (0.55) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28819950 0.85 ECE1 (0.58) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28645426 0.85 ECE1 (0.58) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7003664 0.84 ECE1 (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL14499478 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL20244923 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL13637922 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12076432-B2 Method of repairing oxidatively treated hair CONOPCO, INC. (US) 2024-09-03 US claimed
CN-116987781-A Biomarker for detecting mitochondrial diseases of children and application thereof 浙江省人民医院 2023-11-03 CN claimed
US-20210236402-A1 METHOD OF REPAIRING OXIDATIVELY TREATED HAIR CONOPCO, INC., D/B/A UNILEVER 2021-08-05 US claimed
EP-3773454-A1 METHOD OF REPAIRING OXIDATIVELY TREATED HAIR Unilever PLC (GB) 2021-02-17 EP claimed
CN-112105336-A Method for repairing oxidatively treated hair 荷兰联合利华有限公司 2020-12-18 CN claimed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
WO-2019214965-A1 METHOD OF REPAIRING OXIDATIVELY TREATED HAIR UNILEVER PLC (GB) 2019-11-14 WO claimed
CN-108003105-A A kind of method of synthesized micromolecule amino acid derivativges Ectoin 上海克琴科技有限公司 2018-05-08 CN claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
EP-0950706-B1 D-aminoacylase from Sebekia benihana DAICEL CHEM (JP) 2003-03-05 EP claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
US-20020090713-A1 Enzymatic polypeptide for generating preferential amino acids DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-11 US claimed
EP-1178114-A2 Heat-stable d-aminoacylase Daicel Chemical Industries, Ltd. (JP) 2002-02-06 EP claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
US-6030823-A FOR INDUSTRIAL PRODUCTION OF D-AMINO ACIDS FROM N-ACETYL-D-AMINO ACIDS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-02-29 US claimed
EP-0950706-A2 D-aminoacylase DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-10-20 EP claimed
US-5916774-A PRODUCES D-AMINO ACIDS FROM CORRESPONDING N-ACETYL-D-AMINO ACIDS; ACTIVITY PROMOTED BY COBALT AND CALCIUM IONS BUT INHIBITED BY COPPER, MERCURY AND ZINC IONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-29 US claimed
EP-0896057-A2 D-aminoacylase DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-02-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020090713-A1 Enzymatic polypeptide for generating preferential amino acids DNPEP, NAALAD2, DAO KDM4E 3109/4885MAPT 2308/4885THRB 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.