SCHEMBL468797

SCHEMBL468797

CC(=O)N[C@@H](CC(N)=O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
MAPT P10636 1/20 0.57
THRB P10828 1/20 0.57
ALOX15 P16050 1/20 0.57
NFKB1 P19838 1/20 0.57
PTGS2 P35354 1/20 0.57
THPO P40225 1/20 0.57
RECQL P46063 1/20 0.57
BLM P54132 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ALDH1A1 P00352 2/20 0.55
ECE1 P42892 2/20 0.54
ITGB2 P05107 2/20 0.47
ICAM1 P05362 2/20 0.47
ITGAL P20701 2/20 0.47
GNPAT O15228 1/20 0.46
CA2 P00918 4/20 0.45
CA1 P00915 3/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1204312 1.00 KDM4E (0.57) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL468796 1.00 KDM4E (0.57) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL9438441 0.98 KDM4E (0.55) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL9438442 0.98 KDM4E (0.55) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28819950 0.85 ECE1 (0.58) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL28645426 0.85 ECE1 (0.58) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL7003664 0.84 ECE1 (0.50) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL14499478 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL20244923 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1
SCHEMBL13637922 0.84 KDM4E (0.43) KDM4EMAPTTHRBALOX15NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 440 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100273-A1 METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE NTT株式会社 2026-05-15 WO claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CA) 2025-09-23 US claimed
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
CN-118688333-A Marker related to allergic rhinitis and kit thereof 厦门市迈理奥科技有限公司 2024-09-24 CN claimed
US-12076432-B2 Method of repairing oxidatively treated hair CONOPCO, INC. (US) 2024-09-03 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
EP-4320094-A1 NOVEL MODULATORS OF THE MELATONIN RECEPTORS AS WELL AS METHOD OF MANUFACTURE AND USES THEREOF Cosmas Therapeutics Development Inc. (CA) 2024-02-14 EP claimed
CN-116987781-A Biomarker for detecting mitochondrial diseases of children and application thereof 浙江省人民医院 2023-11-03 CN claimed
CN-113354712-B Enzyme targeting control intramolecular condensation molecular probe and preparation method and application thereof 江苏省原子医学研究所 2023-10-13 CN claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
US-6429220-B1 COMPRISES AN ISOTHIAZOLONE COMPOUND AND AN AMINOCARBOXYLIC ACID KURITA WATER INDUSTRIES LTD. (JP) 2002-08-06 US claimed
US-20020090713-A1 Enzymatic polypeptide for generating preferential amino acids DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-07-11 US claimed
EP-1178114-A2 Heat-stable d-aminoacylase Daicel Chemical Industries, Ltd. (JP) 2002-02-06 EP claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
US-6030823-A FOR INDUSTRIAL PRODUCTION OF D-AMINO ACIDS FROM N-ACETYL-D-AMINO ACIDS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2000-02-29 US claimed
EP-0950706-A2 D-aminoacylase DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-10-20 EP claimed
US-5916774-A PRODUCES D-AMINO ACIDS FROM CORRESPONDING N-ACETYL-D-AMINO ACIDS; ACTIVITY PROMOTED BY COBALT AND CALCIUM IONS BUT INHIBITED BY COPPER, MERCURY AND ZINC IONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-06-29 US claimed
EP-0896057-A2 D-aminoacylase DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 1999-02-10 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020090713-A1 Enzymatic polypeptide for generating preferential amino acids DNPEP, NAALAD2, DAO KDM4E 3109/4885MAPT 2308/4885THRB 2206/4885
US-12421264-B2 Compounds and methods for the treatment of pathogenic Neisseria NMBR, MLEC, BPGM KDM4E 1724/4885MAPT 2341/4885THRB 361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.