SCHEMBL4688291

SCHEMBL4688291

CCCc1cc[nH]c1CC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10538542 0.91 GPR84 (0.34) PRKCIGPR84PDK2
SCHEMBL27763230 0.88 GPR84 (0.33) GPR84PDK2
SCHEMBL28117526 0.84 GPR84 (0.37) GPR84PDK2
SCHEMBL28253637 0.84 GPR84 (0.47) GPR84
SCHEMBL668146 0.83
SCHEMBL7588373 0.81 HTR1A (0.32) GPR84
SCHEMBL27742755 0.81 HTR1A (0.32) GPR84
Pyrrole SCHEMBL27742684 0.81 PBRM1 (0.30) GPR84
SCHEMBL27742663 0.77
SCHEMBL3124388 0.76 GPR84 (0.39) GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017676-A1 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2009-01-21 EP disclosed
EP-1902717-A2 Vasopressin antagonist and oxytocin antagonist Otsuka Pharmaceutical Company, Limited (JP) 2008-03-26 EP disclosed
EP-0620003-B1 VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST OTSUKA PHARMA CO LTD (JP) 2008-01-16 EP disclosed
US-5753644-A Vasopressin antagonist and oxytocin antagonist OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-05-19 US disclosed
US-5622947-A VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-04-22 US disclosed
EP-0620003-A1 VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-19 EP disclosed