Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468834 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NAAANPSR1MAPTMAPK1 | |
| SCHEMBL468820 | 0.94 | NAAA (0.51) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL468819 | 0.94 | NAAA (0.51) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL468854 | 0.94 | NAAA (0.51) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL468856 | 0.94 | NAAA (0.51) | NAAANPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL468849 | 0.90 | MAPT (0.36) | ALDH1A1NAAANPSR1MAPTMAPK1 | |
| SCHEMBL468847 | 0.90 | MAPT (0.36) | ALDH1A1NAAANPSR1MAPTMAPK1 | |
| SCHEMBL19090099 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTSMN1; SMN2ATMPLA2G2C | |
| SCHEMBL468812 | 0.85 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTSMN1; SMN2ATM | |
| SCHEMBL468811 | 0.85 | ALDH1A1 (0.44) | ALDH1A1NPSR1MAPTSMN1; SMN2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42902-E1 | N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use | TRISTRATA, INC. (US) | 2011-11-08 | — | — | US | claimed |