Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687195 | 0.94 | CCR3 (0.47) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4688153 | 0.93 | CCR3 (0.43) | CCR3MAPTTP53KMT2AFLT1 | |
| SCHEMBL4238849 | 0.91 | CCR3 (0.37) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4683563 | 0.89 | CCR3 (0.47) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4687316 | 0.88 | CCR3 (0.36) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4687903 | 0.88 | CCR3 (0.43) | CCR3MAPTMCHR2MCHR1FLT1 | |
| SCHEMBL4689332 | 0.86 | CCR3 (0.42) | CCR3MAPTMCHR1FLT1KDR | |
| SCHEMBL4683722 | 0.86 | MAPT (0.49) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4689244 | 0.85 | CCR3 (0.49) | CCR3MAPTTP53MCHR2MCHR1 | |
| SCHEMBL4234147 | 0.85 | CCR3 (0.38) | CCR3MAPTTP53MCHR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |