Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.43 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | FLT1 | P17948 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688153 | 0.94 | CCR3 (0.43) | CCR3KDRFLT1CCR2MAPT | |
| SCHEMBL4688202 | 0.94 | CCR3 (0.44) | CCR3MCHR2MCHR1KDRFLT1 | |
| SCHEMBL4689230 | 0.91 | CCR3 (0.42) | CCR3MCHR1KDRFLT1POLB | |
| SCHEMBL4236747 | 0.91 | TAS1R3 (0.39) | MCHR2MCHR1KDRFLT1FLT4 | |
| SCHEMBL4687050 | 0.89 | CCR3 (0.46) | CCR3MCHR2MCHR1KDRFLT1 | |
| SCHEMBL4688345 | 0.88 | CCR3 (0.46) | CCR3MCHR2MCHR1KDRFLT1 | |
| SCHEMBL4683563 | 0.88 | CCR3 (0.47) | CCR3MCHR2MCHR1KDRHTR2A | |
| SCHEMBL4232358 | 0.86 | FLT1 (0.36) | CCR3KDRFLT1MAPT | |
| SCHEMBL4689332 | 0.86 | CCR3 (0.42) | CCR3MCHR1KDRFLT1CCR2 | |
| SCHEMBL4229412 | 0.85 | TAS1R3 (0.40) | MCHR2MCHR1KDRFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |