Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683533 | 0.88 | MAPT (0.58) | TOP2AALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7961633 | 0.87 | TDP1 (0.56) | ALDH1A1TDP1KMT2AMAPTRORC | |
| SCHEMBL9996831 | 0.83 | MAPT (0.51) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL10777343 | 0.82 | TDP1 (0.55) | TDP1KMT2AMEN1GAAMAPT | |
| SCHEMBL4687827 | 0.81 | HTT (0.56) | ALDH1A1TDP1KMT2AMEN1GAA | |
| SCHEMBL11045981 | 0.81 | AAK1 (0.49) | TOP2AALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL28950493 | 0.79 | KLKB1 (0.56) | TOP2AALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL10970594 | 0.78 | TSHR (0.54) | ALDH1A1KMT2AMEN1GAA | |
| SCHEMBL4689214 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL10778116 | 0.77 | TDP1 (0.50) | TDP1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |