Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688565 | 0.88 | TOP2A (0.52) | MAPTALDH1A1L3MBTL1POLBTOP2A | |
| SCHEMBL4687827 | 0.79 | HTT (0.56) | MAPTALDH1A1CNR1CNR2POLB | |
| SCHEMBL9794573 | 0.76 | MAPT (0.58) | MAPTHSD17B10ALDH1A1POLBCYP1A2 | |
| SCHEMBL22502142 | 0.75 | C5 (0.65) | MAPTHSD17B10SMPD1CNR2FAAH | |
| SCHEMBL10151472 | 0.75 | ALDH1A1 (0.46) | MAPTHSD17B10SMPD1ALDH1A1L3MBTL1 | |
| SCHEMBL4689214 | 0.75 | ALDH1A1 (0.47) | ALDH1A1POLBCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7961633 | 0.74 | TDP1 (0.56) | MAPTHSD17B10ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL18031232 | 0.74 | KDM4E (0.64) | MAPTHSD17B10SMPD1ALDH1A1POLB | |
| SCHEMBL7785561 | 0.74 | TRPA1 (0.53) | MAPTSMPD1ALDH1A1POLBKDM4E | |
| SCHEMBL28013080 | 0.74 | TDP1 (0.60) | MAPTHSD17B10ALDH1A1POLBFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |