Acetyl Tyrosine Ethyl Ester

Acetyl Tyrosine Ethyl Ester

SCHEMBL468858

CCOC(=O)C(Cc1ccc(O)cc1)NC(C)=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 4/20 0.58
BACE1 P56817 1/20 0.51
GRIA1 P42261 1/20 0.49
KMT2A Q03164 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
TSHR P16473 1/20 0.48
LNPEP Q9UIQ6 1/20 0.48
MDM4 O15151 1/20 0.48
MDM2 Q00987 1/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
FOLH1 Q04609 1/20 0.46
PTGS2 P35354 2/20 0.46
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
LY96 Q9Y6Y9 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyl Tyrosine Ethyl Ester SCHEMBL14370511 1.00 TACR1 (0.58) TACR1BACE1GRIA1KMT2ANPSR1
Acetyl Tyrosine Ethyl Ester SCHEMBL468756 1.00 TACR1 (0.58) TACR1BACE1GRIA1KMT2ANPSR1
Acetyl Tyrosine Ethyl Ester SCHEMBL38655891 0.98 TACR1 (0.56) TACR1BACE1GRIA1KMT2ANPSR1
Acetyl Tyrosine Ethyl Ester SCHEMBL25257912 0.98 TACR1 (0.56) TACR1BACE1GRIA1KMT2ANPSR1
Acetyl Tyrosine Ethyl Ester SCHEMBL2521638 0.98 TACR1 (0.56) TACR1BACE1GRIA1KMT2ANPSR1
SCHEMBL30493599 0.94 TACR1 (0.53) TACR1BACE1GRIA1KMT2ANPSR1
SCHEMBL12453492 0.89 TACR1 (0.59) TACR1
SCHEMBL25669503 0.89 TACR1 (0.59) TACR1
SCHEMBL3046854 0.88 TACR1 (0.52) TACR1GRIA1KMT2ANPSR1TSHR
SCHEMBL3046853 0.88 TACR1 (0.52) TACR1GRIA1KMT2ANPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105628636-B A kind of chymotrypsin vigor testing methods 安徽瑞达健康产业有限公司 2018-08-03 CN claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US claimed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
US-4844884-A TYROSINE DERIVATIVES AND ADENOSINE-5'-PHOSPHATES INDUCHEM AG (CH) 1989-07-04 US claimed
JP-9323915-A None JP disclosed
CN-110698538-A Cyclic peptide compound based on tyrosine coupling and preparation and application thereof 浙江工业大学 2020-01-17 CN disclosed
CN-108530617-A A kind of branched polyethylene glycol Heterobifunctional derivative, preparation method and its two-component bio-related substance conjugate 厦门赛诺邦格生物科技股份有限公司 2018-09-14 CN disclosed
CN-105628636-B A kind of chymotrypsin vigor testing methods 安徽瑞达健康产业有限公司 2018-08-03 CN disclosed
CN-103534349-B Polypeptide with endopeptidase activity and encode its polynucleotides 诺维信公司 2017-07-21 CN disclosed
EP-1534269-B1 OXIME CONJUGATES AND METHODS FOR THEIR FORMATION AND USE GEN HOSPITAL CORP (US) 2013-10-30 EP disclosed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US disclosed
EP-0048433-A2 Novel amidine compounds, process for producing same and anti-complement agent comprising them TORII & CO., LTD. (JP) 1982-03-31 EP disclosed
US-4298395-A HALOGENATED PYRIMIDINE ACTIVATOR FOR BINDING LIGANDS BAYER AKTIENGESELLSCHAFT (DE) 1981-11-03 US disclosed
US-4214093-A PROTEOLYTIC ENZYME INHIBITORS TORII & CO., LTD. (JP) 1980-07-22 US disclosed
US-4195128-A LIGAND BOUND TO CARRIER THROUGH PYRIMIDINE DERIVATIVE BAYER AKTIENGESELLSCHAFT (DE) 1980-03-25 US disclosed
US-4182897-A ENZYME INHIBITORS FOR PROTEOLYTIC ENZYMES TORII & CO., LTD. (JP) 1980-01-08 US disclosed
US-4144128-A Polymeric carrier bound ligands BAYER AKTIENGESELLSCHAFT (DE) 1979-03-13 US disclosed
US-4030977-A Method for purification of physiologically active substance using enzyme-enzyme inhibitor system ONO PHARMACEUTICAL CO., LTD. (JA) 1977-06-21 US disclosed
US-3932618-A REACTION PRODUCT OF BLOOD AND A PROTEASE OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JA) 1976-01-13 US disclosed