Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.58 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetyl Tyrosine Ethyl Ester SCHEMBL468858 | 1.00 | TACR1 (0.58) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL468756 | 1.00 | TACR1 (0.58) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL38655891 | 0.98 | TACR1 (0.56) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL25257912 | 0.98 | TACR1 (0.56) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| Acetyl Tyrosine Ethyl Ester SCHEMBL2521638 | 0.98 | TACR1 (0.56) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| SCHEMBL30493599 | 0.94 | TACR1 (0.53) | TACR1BACE1GRIA1KMT2ANPSR1 | |
| SCHEMBL12453492 | 0.89 | TACR1 (0.59) | TACR1 | |
| SCHEMBL25669503 | 0.89 | TACR1 (0.59) | TACR1 | |
| SCHEMBL3046854 | 0.88 | TACR1 (0.52) | TACR1GRIA1KMT2ANPSR1TSHR | |
| SCHEMBL3046853 | 0.88 | TACR1 (0.52) | TACR1GRIA1KMT2ANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7282606-B2 | Process for preparation of tamsulosin and its aralkylamine derivatives | WELL-BEING BIOCHEMICAL CORP. (TW) | 2007-10-16 | — | — | US | disclosed |
| US-20070015939-A1 | Process for preparation of tamsulosin and its aralkylamine derivatives | WELL-BEING BIOCHEMICAL CORP (TW) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015939-A1 | Process for preparation of tamsulosin and its aralkylamine derivatives | ADRB1, ADRA2B, ADRA2A | TACR1 272/4885BACE1 2616/4885GRIA1 3644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.