Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | HIPK4 | Q8NE63 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.31 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854914 | 0.64 | KDM4E (0.31) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL5377839 | 0.64 | KDM4E (0.31) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL5387190 | 0.64 | KDM4E (0.53) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL31722003 | 0.64 | CSF1R (0.43) | CSF1RFLT1KDRFLT3HIPK4 | |
| SCHEMBL18583289 | 0.64 | ADRA2A (0.41) | CSF1RFLT1KDRFLT3HIPK4 | |
| SCHEMBL131949 | 0.63 | — | — | |
| SCHEMBL2679046 | 0.63 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL30987223 | 0.62 | MAPT (0.60) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL28563540 | 0.62 | MAPT (0.60) | KDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL11092129 | 0.60 | CSF1R (0.39) | CSF1RFLT1KDRFLT3HIPK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638934-B1 | 3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE | LILLY CO ELI (US) | 2008-01-09 | — | — | EP | disclosed |